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omaveloxolone
Sign in to saveOmaveloxolone, sold under the brand name Skyclarys, is a medication used for the treatment of Friedreich's ataxia. It is taken by mouth.
Chemical data
- Formula
- C33H44F2N2O3
- Molecular weight
- 554.7 g/mol
- IUPAC name
- N-[(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicen-4a-yl]-2,2-difluoropropanamide
via PubChem
Wikidata facts
- Subclass of
- organofluorine
- Mass
- 554.332
Show 5 more facts
- chemical formula
- C₃₃H₄₄F₂N₂O₃
- isomeric SMILES
- C[C@@]12CC[C@]3(CCC(C[C@H]3[C@H]1C(=O)C=C4[C@]2(CC[C@@H]5[C@@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)NC(=O)C(C)(F)F
- canonical SMILES
- CC1(CCC2(CCC3(C(C2C1)C(=O)C=C4C3(CCC5C4(C=C(C(=O)C5(C)C)C#N)C)C)C)NC(=O)C(C)(F)F)C
- Commons category
- Omaveloxolone
- medical condition treated
- Friedreich ataxia
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Mechanism of action
- History
- Society and culture
- Legal status
- References
- External links
Omaveloxolone, sold under the brand name Skyclarys, is a medication used for the treatment of Friedreich's ataxia. It is taken by mouth.
The most common side effects include an increase in alanine transaminase and an increase of aspartate aminotransferase, which can be signs of liver damage, headache, nausea, abdominal pain, fatigue, diarrhea and musculoskeletal pain.
Excerpted from Wikipedia’s “omaveloxolone” article, available under the CC BY-SA 4.0 licence.