Opelousas

Opelousas (/ˌɒpəˈluːsəs/; French: Les Opélousas; Spanish: Los Opeluzás) is a small city in and the parish seat of St. Landry Parish, Louisiana, United States. Interstate 49 and U.S. Route 190 were constructed with a junction here. The U.S. Census Bureau’s 2025 estimated population for Opelousas is 15,098. According to the 2020 census, Opelousas has a population of 15,786, a 6.53 percent decline since the 2010 census, which had recorded a population of 16,634. Opelousas is the principal city for the Opelousas-Eunice Micropolitan Statistical Area, which had an estimated population of 80,808 in 2020. Opelousas is also the fourth largest city in the Lafayette-Acadiana Combined Statistical Area, which has a population of 537,947.

Historically an area of settlement by French and Spanish Creoles, Creoles of color, and Acadians, Opelousas is the center of zydeco music. It celebrates its heritage at the Creoles of Color Heritage Folklife Center, one of the destinations on the new Louisiana African-American Heritage Trail. It is also the location of the Evangeline Downs Racetrack and Casino.