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GeneQ18055689· pop 5· linked from 338 articles

Also known as OR9-26, OR9-B, olfactory receptor family 1 subfamily B member 1 (gene/pseudogene), olfactory receptor family 1 subfamily B member 1

Olfactory receptor 1B1 is a protein that in humans is encoded by the OR1B1 gene. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family i

Gene data

OR1B1
Name
olfactory receptor family 1 subfamily B member 1
Type
protein-coding
Aliases
OR9-26, OR9-B

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015].

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Gene · Ensembl

olfactory receptor family 1 subfamily B member 1

Symbol
OR1B1
Biotype
Protein coding
Organism
Homo sapiens
Location
9:122,628,125-122,657,627
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
17479
genomic start
125390858
cytogenetic location
9q33.2
genomic end
125391852
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via Wikidata · CC0

~1 min read

Article

5 sections
Contents
  • Ligands
  • See also
  • References
  • Further reading
  • External links

Olfactory receptor 1B1 is a protein that in humans is encoded by the OR1B1 gene. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

==Ligands== As of 2024, OR1B1 was an orphan receptor, meaning that no odorants have been identified which bind to it.

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