PA2G4

Name

proliferation-associated 2G4

Type

protein-coding

Position

56,104,349–56,116,329 (+)

Aliases

EBP1, HG4-1, ITAF45, p38-2G4

Ensembl

ENSG00000170515

RefSeq RNA

NM_006191.3

RefSeq protein

NP_006182.2

This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

proliferation-associated 2G4

Symbol

PA2G4

Biotype

Protein coding

Organism

Homo sapiens

Location

12:56,104,349-56,116,329

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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