PALM

Also known as paralemmin, PALM1

Paralemmin is a protein that in humans is encoded by the PALM gene.

Gene data

PALM

Name: paralemmin
Type: protein-coding
Position: 708,935–748,329 (+)
Aliases: PALM1
Ensembl: ENSG00000099864
RefSeq RNA: NM_001040134.2, NM_002579.3, XM_005259565.5, XM_005259566.5, XM_017026850.3
RefSeq protein: NP_001035224.1, NP_002570.2, XP_005259622.1, XP_005259623.1, XP_016882339.1

This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway regulation of cell shape positive regulation of filopodium assembly positive regulation of filopodium assembly synapse maturation synapse maturation negative regulation of dopamine receptor signaling pathway cellular response to electrical stimulus

Molecular function

protein binding D3 dopamine receptor binding

Cellular component

nucleoplasm cytoplasm plasma membrane plasma membrane plasma membrane cytoplasmic side of plasma membrane postsynaptic density membrane

via MyGene.info

Wikidata facts

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HomoloGene ID: 1937
exact match: identifiers.org/ncbigene/5064
genomic end: 748329
genomic start: 708935
cytogenetic location: 19p13.3

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Paralemmin is a protein that in humans is encoded by the PALM gene.

This gene encodes a member of the paralemmin protein family. Other members of this family include CAP-23, GAP-43, MARCKS, and MacMARCKS. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.