PANX1
Sign in to saveAlso known as MRS1, PX1, UNQ2529, pannexin 1, OOMD7, Pannexin1
Pannexin 1 is a protein in humans that is encoded by the PANX1 gene.
Gene data
PANX1- Name
- pannexin 1
- Type
- protein-coding
- Position
- 94,128,828–94,185,019 (+)
- Aliases
- MRS1, OOMD7, OZEMA7, PX1, UNQ2529
- Ensembl
- ENSG00000110218
- RefSeq RNA
- NM_015368.4, XM_011542734.3, XM_047426702.1, XM_054368280.1, XM_054368281.1
- RefSeq protein
- NP_056183.2, XP_011541036.1, XP_047282658.1, XP_054224255.1, XP_054224256.1
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
pannexin 1
- Symbol
- PANX1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:94,128,828-94,185,019
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 49416
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/24145
- genomic end
- 93915138
- genomic start
- 94128841
- chromosome
- human chromosome 11
- cytogenetic location
- 11q21
- expressed in
- right coronary artery
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Clinical relevance
- References
- Further reading
Pannexin 1 is a protein in humans that is encoded by the PANX1 gene.
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
Excerpted from Wikipedia’s “PANX1” article, available under the CC BY-SA 4.0 licence.