PARD6A
Sign in to saveAlso known as PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40, par-6 family cell polarity regulator alpha
Gen der Spezies Homo sapiens
Gene data
PARD6A- Name
- par-6 family cell polarity regulator alpha
- Type
- protein-coding
- Position
- 67,660,350–67,664,266 (+)
- Aliases
- PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
- Ensembl
- ENSG00000102981
- RefSeq RNA
- NM_001037281.2, NM_016948.3, XM_005255977.4, XM_011523095.3, XM_047434186.1
- RefSeq protein
- NP_001032358.1, NP_058644.1, XP_005256034.1, XP_011521397.1, XP_047290142.1
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
par-6 family cell polarity regulator alpha
- Symbol
- PARD6A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:67,660,350-67,664,266
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PARD6A PDB 1wmh.png
Show 8 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 9661
- exact match
- identifiers.org/ncbigene/50855
- genomic end
- 67662774
- genomic start
- 67694849
- chromosome
- human chromosome 16
- cytogenetic location
- 16q22.1
- expressed in
- triceps brachii muscle
Sources (3)
via Wikidata · CC0