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Parvoviridae
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Parvoviridae

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Also known as Parvovirus

Parvoviruses are a family of animal viruses that constitute the family Parvoviridae. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the protein the viral capsid is made of. The coding portion of the genome is flanked by telomeres at each end that form into hairpin loops that are important during replication. Parvovirus virions are small compared to most viruses, at 23–28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface.

Species

FAMILY

  1. KingdomViruses
  2. PhylumCossaviricota
  3. ClassQuintoviricetes
  4. OrderPiccovirales
  5. FamilyParvoviridae
Observations recorded19,572

Die Familie Parvoviridae (Parvoviren) umfasst Spezies von Viren, die ein einzelsträngiges DNA-Genom tragen. Die Virionen (Viruspartikel) der Parvoviridae haben einen Durchmesser zwischen 18 und 26 nm; da sie damit zu den kleinsten Viren zählen, leitet sich ihr Name von lateinisch parvus ‚klein‘ ab. Parvoviren sind unbehüllt, wodurch sie sehr resistent gegen äußere Einflüsse sind. Die Familie Parvoviridae wird nach der derzeitigen Master Species List #36 des International Committee on Taxonomy of Viruses (ICTV) in drei Unterfamilien aufgeteilt: Parvovirinae, Densovirinae und Hamaparvovirinae.[3] Schemazeichnung eines Virions der Familie Parvoviridae, Querschnitt und Seitenansicht Inhaltsverzeichnis 1 Unterfamilie Parvovirinae 1.1 Genus Dependoparvovirus 1.2 Genus Erythroparvovirus 1.3 Genus Protoparvovirus 1.4 Genus Tetraparvovirus 1.5 Genus Copiparvovirus 1.6 Genus Bocaparvovirus 2 Unterfamilie Densovirinae 3 Unterfamilie Hamaparvovirinae 4 Weblinks 5 Einzelnachweise Unterfamilie Parvovirinae Zu den Parvovirinae, welche ausschließlich Wirbeltiere infizieren, zählen die Genera Amdoparvovirus (alias Amdovirus), Artiparvovirus, Aveparvovirus, Bocaparvovirus (alias Bocavirus), Copiparv

via GBIF

Research

24,474 papers

via PubMed

Wikidata facts

Instance of
taxon
Image
Parvovirus in Blood.jpg
Show 7 more facts
taxon name
Parvoviridae
taxon rank
family
topic's main category
Category:Parvoviruses
Commons category
Parvoviridae
taxon common name
Parvo-viruses
ICTV virus genome composition
single-stranded DNA virus
Sources (3)

via Wikidata · CC0

~21 min read

Encyclopedic overview

13 sections
Contents
  • Genome
  • Structure
  • Life cycle
  • Evolution
  • Classification
  • Disease
  • Use in medicine
  • History
  • Etymology
  • See also
  • Citations
  • General and cited references
  • External links

Parvoviruses are a family of animal viruses that constitute the family Parvoviridae. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the protein the viral capsid is made of. The coding portion of the genome is flanked by telomeres at each end that form into hairpin loops that are important during replication. Parvovirus virions are small compared to most viruses, at 23–28 nanometers in diameter, and contain the genome enclosed in an icosahedral capsid that has a rugged surface.

Parvoviruses enter a host cell by endocytosis, travelling to the nucleus where they wait until the cell enters its replication stage. At that point, the genome is uncoated and the coding portion is replicated. Viral messenger RNA (mRNA) is then transcribed and translated, resulting in NS1 initiating replication. During replication, the hairpins repeatedly unfold, are replicated, and refold to change the direction of replication to progress back and forth along the genome in a process called rolling hairpin replication that produces a molecule containing numerous copies of the genome. Progeny ssDNA genomes are excised from this concatemer and packaged into capsids. Mature virions leave the cell by exocytosis or lysis.

Excerpted from Wikipedia’s “Parvoviridae” article, available under the CC BY-SA 4.0 licence.

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