PCGF6
Sign in to saveAlso known as MBLR, RNF134, polycomb group ring finger 6
Polycomb group RING finger protein 6 is a protein that in humans is encoded by the PCGF6 gene.
Gene data
PCGF6- Name
- polycomb group ring finger 6
- Type
- protein-coding
- Position
- 103,302,796–103,351,150 (−)
- Aliases
- MBLR, RNF134
- Ensembl
- ENSG00000156374
- RefSeq RNA
- NM_001011663.2, NM_032154.4, XM_047425832.1, XM_047425833.1, XM_047425834.1
- RefSeq protein
- NP_001011663.1, NP_115530.2, XP_047281788.1, XP_047281789.1, XP_047281790.1
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
polycomb group ring finger 6
- Symbol
- PCGF6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:103,302,796-103,351,150
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PCGF6 PDB 2djb.png
Show 7 more facts
- HomoloGene ID
- 12378
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/84108
- chromosome
- human chromosome 10
- genomic start
- 105062553
- genomic end
- 103351144
- cytogenetic location
- 10q24.33
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Polycomb group RING finger protein 6 is a protein that in humans is encoded by the PCGF6 gene.
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Excerpted from Wikipedia’s “PCGF6” article, available under the CC BY-SA 4.0 licence.