PCGF6
Sign in to saveAlso known as MBLR, RNF134, polycomb group ring finger 6
Polycomb group RING finger protein 6 is a protein that in humans is encoded by the PCGF6 gene.
Gene data
PCGF6- Name
- polycomb group ring finger 6
- Type
- protein-coding
- Aliases
- MBLR, RNF134
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein PCGF6 PDB 2djb.png
Show 5 more facts
- HomoloGene ID
- 12378
- exact match
- identifiers.org/ncbigene/84108
- genomic start
- 105062553
- genomic end
- 103351144
- cytogenetic location
- 10q24.33
Sources (3)
via Wikidata · CC0
~1 min read
Article
2 sectionsContents
- References
- Further reading
Polycomb group RING finger protein 6 is a protein that in humans is encoded by the PCGF6 gene.
The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.