PDCD10
Sign in to saveAlso known as CCM3, TFAR15, programmed cell death 10
Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene.
Gene data
PDCD10- Name
- programmed cell death 10
- Type
- protein-coding
- Position
- 167,677,517–167,735,039 (−)
- Aliases
- CCM3, TFAR15
- Ensembl
- ENSG00000114209
- RefSeq RNA
- NM_001439202.1, NM_001439204.1, NM_001439205.1, NM_007217.4, NM_145859.2
- RefSeq protein
- NP_001426131.1, NP_001426133.1, NP_001426134.1, NP_009148.2, NP_665858.1
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
programmed cell death 10
- Symbol
- PDCD10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:167,677,517-167,735,039
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
6 sectionsContents
- Function
- Gene
- Interactions
- References
- Further reading
- External links
Programmed cell death protein 10 is a protein that in humans is encoded by the PDCD10 gene.
== Function ==
Excerpted from Wikipedia’s “PDCD10” article, available under the CC BY-SA 4.0 licence.