Gene data
PDCD5- Name
- programmed cell death 5
- Type
- protein-coding
- Position
- 32,581,062–32,587,453 (+)
- Aliases
- TFAR19
- Ensembl
- ENSG00000105185
- RefSeq RNA
- NM_004708.4, XM_005259392.6, XM_054322581.1
- RefSeq protein
- NP_004699.1, XP_005259449.1, XP_054178556.1
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010].
Gene Ontology
Biological process
T cell activationregulation of apoptotic processpositive regulation of apoptotic processcellular response to transforming growth factor beta stimuluspositive regulation of signal transduction by p53 class mediatorpositive regulation of intrinsic apoptotic signaling pathway by p53 class mediatornegative regulation of protein folding
Molecular function
via MyGene.info
Gene · Ensembl
programmed cell death 5
- Symbol
- PDCD5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:32,581,062-32,587,453
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PDCD5 PDB 2cru.png
Show 8 more facts
- HomoloGene ID
- 10506
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9141
- chromosome
- human chromosome 19
- genomic start
- 32581190
- genomic end
- 32587453
- cytogenetic location
- 19q13.11
- expressed in
- anterior cingulate cortex
Sources (4)
via Wikidata · CC0