PGA5
Sign in to saveAlso known as Pg5, pepsinogen 5, group I (pepsinogen A), pepsinogen A5
protein-coding gene in the species Homo sapiens
In the Vinony graph
Vinony's link graph records 3 inbound references to PGA5, and connects out to Q180686, human chromosome 11 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 11.
Vinony links it to 6 Wikipedia language editions.
Gene data
PGA5- Name
- pepsinogen A5
- Type
- protein-coding
- Aliases
- Pg5
This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer. [provided by RefSeq, Jul 2015].
via MyGene.info
Gene · Ensembl
pepsinogen A5
- Symbol
- PGA5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:61,241,175-61,251,444
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein PGA5 PDB 1flh.png
Show 5 more facts
- HomoloGene ID
- 68135
- exact match
- identifiers.org/ncbigene/5222
- genomic start
- 61241175
- genomic end
- 61251444
- cytogenetic location
- 11q12.2
Sources (4)
via Wikidata · CC0