Key facts
- Born
- ( 1944-06-06 ) June 6, 1944 (age 81) , Falmouth, Kentucky , U.S.
- Education
- Union Commonwealth University ( BA ) University of Illinois at Urbana–Champaign ( PhD )
- Spouse
- Ann Holcombe ( married</span>"}]]}'>m. 1964 )
- Awards
- NAS Award in Molecular Biology (1980) Louisa Gross Horwitz Prize (1988) Dickson Prize (1991) Nobel Prize (1993) Novartis-Drew Award (2003) National Medal of Science (2004)
- Fields
- Biologist
- Institutions
- Caltech Cold Spring Harbor Laboratory MIT
- Doctoral students
- Connie Cepko Andrew Fire Melissa J. Moore Richard Carthew
- Website
- web .mit .edu /sharplab
via Wikipedia infobox
Article
Phillip Allen Sharp (born June 6, 1944) is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for "the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence". He was awarded the 2015 Othmer Gold Medal.
Sharp's current research focuses on small RNAs and other types of non-coding RNAs. His laboratory works to identify the target mRNAs of microRNAs (miRNAs), and has discovered a class of miRNAs that are produced from sequences adjacent to transcription start sites. His laboratory also studies how miRNA gene regulation functions in angiogenesis and cellular stress.
Gallery (3)
Connections
Categories
1944 birthsAmerican fellows of the Royal SocietyAmerican geneticistsAmerican Nobel laureatesCalifornia Institute of Technology facultyForeign members of the Royal SocietyLiving peopleMembers of the American Philosophical SocietyMembers of the European Molecular Biology OrganizationMembers of the National Academy of MedicineMembers of the United States National Academy of Sciences