Phosphoketolase
Sign in to saveAlso known as D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (phosphate-acetylating), xylulose-5-phosphate phosphoketolase, D-xylulose-5-phosphate D-glyceraldehyde-3-phosphate-lyase (adding phosphate; acetyl-phosphate-forming)
The enzyme phosphoketolase() catalyzes the chemical reactions
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The enzyme phosphoketolase() catalyzes the chemical reactions D-xylulose 5-phosphate + phosphate \rightleftharpoons acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O () D-fructose 6-phosphate + phosphate \rightleftharpoons acetyl phosphate + D-erythrose 4-phosphate + H2O (EC 4.1.2.22) D-sedoheptulose 7-phosphate + phosphate \rightleftharpoons acetyl phosphate + D-ribose 5-phosphate + H2O
Phosphoketolase is considered a promiscuous enzyme because it was demonstrated to use 3 different sugar phosphates as substrates. In a recent genetic study, more than 150 putative phosphoketolase genes exhibiting varying catalytic properties were found in 650 analyzed bacterial genomes.
Excerpted from Wikipedia’s “Phosphoketolase” article, available under the CC BY-SA 4.0 licence.