The enzyme phosphoketolase() catalyzes the chemical reactions
The enzyme phosphoketolase() catalyzes the chemical reactions D-xylulose 5-phosphate + phosphate \rightleftharpoons acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O () D-fructose 6-phosphate + phosphate \rightleftharpoons acetyl phosphate + D-erythrose 4-phosphate + H2O (EC 4.1.2.22) D-sedoheptulose 7-phosphate + phosphate \rightleftharpoons acetyl phosphate + D-ribose 5-phosphate + H2O
Phosphoketolase is considered a promiscuous enzyme because it was demonstrated to use 3 different sugar phosphates as substrates. In a recent genetic study, more than 150 putative phosphoketolase genes exhibiting varying catalytic properties were found in 650 analyzed bacterial genomes.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).