PIGW
Sign in to saveAlso known as Gwt1, HPMRS5, phosphatidylinositol glycan anchor biosynthesis class W
Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene.
Gene data
PIGW- Name
- phosphatidylinositol glycan anchor biosynthesis class W
- Type
- protein-coding
- Aliases
- Gwt1, HPMRS5
The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017].
via MyGene.info
Gene · Ensembl
phosphatidylinositol glycan anchor biosynthesis class W
- Symbol
- PIGW
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR17_7_CTG4:769,924-774,214
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 6243
- exact match
- identifiers.org/ncbigene/284098
- genomic start
- 36534987
- genomic end
- 34895159
- cytogenetic location
- 17q12
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene.
==Function==