PIGW
Sign in to saveAlso known as Gwt1, HPMRS5, phosphatidylinositol glycan anchor biosynthesis class W
Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene.
Gene data
PIGW- Name
- phosphatidylinositol glycan anchor biosynthesis class W
- Type
- protein-coding
- Position
- 36,534,981–36,542,354 (+)
- Aliases
- Gwt1, HPMRS5
- Ensembl
- ENSG00000275600
- RefSeq RNA
- NM_001346754.2, NM_001346755.2, NM_178517.5
- RefSeq protein
- NP_001333683.1, NP_001333684.1, NP_848612.2
The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
phosphatidylinositol glycan anchor biosynthesis class W
- Symbol
- PIGW
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR17_7_CTG4:769,924-774,214
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 6243
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/284098
- chromosome
- human chromosome 17
- genomic start
- 36534987
- genomic end
- 34895159
- cytogenetic location
- 17q12
- expressed in
- gonad
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene.
==Function==
Excerpted from Wikipedia’s “PIGW” article, available under the CC BY-SA 4.0 licence.