PIK3C3

Also known as VPS34, hVps34, phosphatidylinositol 3-kinase catalytic subunit type 3

Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme subunit that in humans is encoded by the PIK3C3 gene. It's a class III phosphoinositide 3-kinase.

In the Vinony graph

Within Vinony's link graph, PIK3C3 is referenced by 10 other articles, and connects out to PubMed, human chromosome 18 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 18.

Its subject is documented across 6 Wikipedia language editions.

Gene data

PIK3C3

Name: phosphatidylinositol 3-kinase catalytic subunit type 3
Type: protein-coding
Position: 41,955,195–42,087,830 (+)
Aliases: VPS34, Vps34, hVps34
Ensembl: ENSG00000078142
RefSeq RNA: NM_001308020.2, NM_002647.4, XM_047437549.1, XM_047437550.1, XM_047437551.1
RefSeq protein: NP_001294949.1, NP_002638.2, XP_047293505.1, XP_047293506.1, XP_047293507.1

Enables 1-phosphatidylinositol-3-kinase activity. Involved in early endosome to late endosome transport and regulation of cytokinesis. Acts upstream of or within autophagy and protein lipidation. Located in autolysosome; late endosome; and midbody. [provided by Alliance of Genome Resources, Apr 2022]

Pathways

Inositol phosphate metabolism - Homo sapiens (human)Phosphatidylinositol signaling system - Homo sapiens (human)Autophagy - other - Homo sapiens (human)Autophagy - animal - Homo sapiens (human)Phagosome - Homo sapiens (human)Apelin signaling pathway - Homo sapiens (human)Alzheimer disease - Homo sapiens (human)Amyotrophic lateral sclerosis - Homo sapiens (human)Huntington disease - Homo sapiens (human)Spinocerebellar ataxia - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

phosphatidylinositol 3-kinase catalytic subunit type 3

Symbol: PIK3C3
Biotype: Protein coding
Organism: Homo sapiens
Location: 18:41,955,195-42,087,830
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein PIK3C3 PDB 3IHY.png

Show 7 more facts

HomoloGene ID: 1986
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/5289
genomic end: 39667794
genomic start: 41955234
chromosome: human chromosome 18
cytogenetic location: 18q12.3

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

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Contents

References
Further reading

Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme subunit that in humans is encoded by the PIK3C3 gene. It's a class III phosphoinositide 3-kinase.

==References==

Excerpted from Wikipedia’s “PIK3C3” article, available under the CC BY-SA 4.0 licence.