PIK3CG
Sign in to saveAlso known as PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, IMD97
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PIK3CG gene.
Gene data
PIK3CG- Name
- phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
- Type
- protein-coding
- Position
- 106,865,278–106,908,980 (+)
- Aliases
- IMD97, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K
- Ensembl
- ENSG00000105851
- RefSeq RNA
- NM_001282426.2, NM_001282427.2, NM_002649.3, XM_005250443.4, XM_011516316.2
- RefSeq protein
- NP_001269355.1, NP_001269356.1, NP_002640.2, XP_005250500.1, XP_011514618.1
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
- Symbol
- PIK3CG
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:106,865,278-106,908,980
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 68269
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5294
- genomic end
- 106908980
- genomic start
- 106505723
- chromosome
- human chromosome 7
- cytogenetic location
- 7q22.3
- expressed in
- visceral pleura
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PIK3CG gene.
== Function ==
Excerpted from Wikipedia’s “PIK3CG” article, available under the CC BY-SA 4.0 licence.