PLA2G7
Sign in to saveAlso known as LDL-PLA2, LP-PLA2, PAFAD, PAFAH, Lipoprotein-associated phospholipase A2, phospholipase A2 group VII
protein-coding gene in the species Homo sapiens
Gene data
PLA2G7- Name
- phospholipase A2 group VII
- Type
- protein-coding
- Position
- 46,698,431–46,735,728 (−)
- Aliases
- LDL-PLA2, LP-PLA2, PAFAD, PAFAH
- Ensembl
- ENSG00000146070
- RefSeq RNA
- NM_001168357.2, NM_005084.4, XM_005249408.5, XM_047419359.1, XM_047419360.1
- RefSeq protein
- NP_001161829.1, NP_005075.3, XP_005249465.1, XP_047275315.1, XP_047275316.1
The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2009].
Gene Ontology
Biological process
Molecular function
1-alkyl-2-acetylglycerophosphocholine esterase activity1-alkyl-2-acetylglycerophosphocholine esterase activity1-alkyl-2-acetylglycerophosphocholine esterase activity1-alkyl-2-acetylglycerophosphocholine esterase activityA2-type glycerophospholipase activityprotein bindingphospholipid bindinghydrolase activity, acting on ester bonds
Pathways
via MyGene.info
Gene · Ensembl
phospholipase A2 group VII
- Symbol
- PLA2G7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:46,698,431-46,735,728
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PLA2G7 PDB 3D59.png
Show 7 more facts
- HomoloGene ID
- 3725
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/7941
- genomic end
- 46703430
- genomic start
- 46671938
- chromosome
- human chromosome 6
- cytogenetic location
- 6p12.3
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