PLEKHG4
Sign in to saveAlso known as ARHGEF44, PRTPHN1, SCA4, pleckstrin homology and RhoGEF domain containing G4
Puratrophin-1 is a protein that in humans is encoded by the PLEKHG4 gene.
Gene data
PLEKHG4- Name
- pleckstrin homology and RhoGEF domain containing G4
- Type
- protein-coding
- Position
- 67,277,510–67,289,499 (+)
- Aliases
- ARHGEF44, PRTPHN1, SCA4
- Ensembl
- ENSG00000196155
- RefSeq RNA
- NM_001129727.3, NM_001129728.2, NM_001129729.3, NM_001129731.3, NM_015432.3
- RefSeq protein
- NP_001123199.1, NP_001123200.1, NP_001123201.1, NP_001123203.1, XP_011521287.1
The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
pleckstrin homology and RhoGEF domain containing G4
- Symbol
- PLEKHG4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:67,277,510-67,289,499
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Puratrophin-1 is a protein that in humans is encoded by the PLEKHG4 gene.
==References==
Excerpted from Wikipedia’s “PLEKHG4” article, available under the CC BY-SA 4.0 licence.