PLXNA2
Sign in to saveAlso known as OCT, PLXN2, plexin A2
Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene.
Gene data
PLXNA2- Name
- plexin A2
- Type
- protein-coding
- Position
- 208,022,242–208,244,850 (−)
- Aliases
- OCT, PLXN2
- Ensembl
- ENSG00000076356
- RefSeq RNA
- NM_025179.4, XM_005273164.4, XM_005273165.5, XM_054337094.1, XM_054337095.1
- RefSeq protein
- NP_079455.3, XP_005273221.1, XP_005273222.1, XP_054193069.1, XP_054193070.1
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
plexin A2
- Symbol
- PLXNA2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:208,022,242-208,244,850
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 56427
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5362
- genomic end
- 208244384
- genomic start
- 208195587
- chromosome
- human chromosome 1
- cytogenetic location
- 1q32.2
- expressed in
- right coronary artery
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene.
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.
Excerpted from Wikipedia’s “PLXNA2” article, available under the CC BY-SA 4.0 licence.