PNPLA3
Sign in to saveAlso known as ADPN, C22orf20, iPLA(2)epsilon, patatin like phospholipase domain containing 3
Patatin-like phospholipase domain-containing protein 3 (PNPLA3), also known as adiponutrin (ADPN), acylglycerol O-acyltransferase or calcium-independent phospholipase A2-epsilon (iPLA2-epsilon) is an enzyme that in humans is encoded by the PNPLA3 gene.
Gene data
PNPLA3- Name
- patatin like domain 3, 1-acylglycerol-3-phosphate O-acyltransferase
- Type
- protein-coding
- Aliases
- ADPN, C22orf20, iPLA(2)epsilon
The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 11883
- exact match
- identifiers.org/ncbigene/80339
- genomic end
- 44360368
- genomic start
- 43923792
- cytogenetic location
- 22q13.31
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Function
- Genomics
- Biochemistry
- Clinical relevance
- References
- Further reading
Patatin-like phospholipase domain-containing protein 3 (PNPLA3), also known as adiponutrin (ADPN), acylglycerol O-acyltransferase or calcium-independent phospholipase A2-epsilon (iPLA2-epsilon) is an enzyme that in humans is encoded by the PNPLA3 gene.
== Function ==