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protobiont
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protobiont

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Also known as Protocell

A protocell (or protobiont) is a self-organized, membrane-bound or membraneless compartment that concentrates biomolecules, proposed as a rudimentary precursor to cells during the origin of life. A central question in evolution is how simple protocells first arose and how their progeny could diversify, thus enabling the accumulation of novel biological emergences over time (i.e. biological evolution). Although a functional protocell has not yet been achieved in a laboratory setting, the goal to understand the process appears well within reach.

~32 min read

Article

19 sections
Contents
  • Overview
  • Selectivity for compartmentalization
  • Vesicles, micelles and membranes
  • Membrane transport
  • Biomolecular condensates as protocells
  • Suitable prebiotic environments
  • Hydrothermal systems
  • Montmorillonite bubbles
  • Membraneless droplets
  • Coacervates
  • Sexual reproduction
  • Artificial models
  • Langmuir–Blodgett deposition
  • Jeewanu protocells
  • Bio-like structures
  • Analogous Research: Fuel Cells
  • Ethics, controversy, and research considerations
  • See also
  • References

A protocell (or protobiont) is a self-organized, membrane-bound or membraneless compartment that concentrates biomolecules, proposed as a rudimentary precursor to cells during the origin of life. A central question in evolution is how simple protocells first arose and how their progeny could diversify, thus enabling the accumulation of novel biological emergences over time (i.e. biological evolution). Although a functional protocell has not yet been achieved in a laboratory setting, the goal to understand the process appears well within reach.

A protocell is a pre-cell in abiogenesis, and was a contained system consisting of simple biologically relevant molecules like ribozymes, and encapsulated in a simple membrane structure – isolating the entity from the environment and other individuals – thought to consist of simple fatty acids, mineral structures, or rock-pore structures.

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