PUM1

Name

pumilio RNA binding family member 1

Type

protein-coding

Position

30,931,505–31,065,991 (−)

Aliases

HSPUM, NEDMSF, PUMH, PUMH1, PUML1, SCA47

Ensembl

ENSG00000134644

RefSeq RNA

NM_001020658.2, NM_014676.3

RefSeq protein

NP_001018494.1, NP_055491.1

This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

pumilio RNA binding family member 1

Symbol

PUM1

Biotype

Protein coding

Organism

Homo sapiens

Location

1:30,931,505-31,065,991

Strand

Reverse (−)

Assembly

GRCh38