PXDN
Sign in to saveAlso known as COPOA, D2S448, D2S448E, MG50, PRG2, PXN, VPO, peroxidasin
Peroxidasin homolog is a protein that in humans is encoded by the PXDN gene.
Gene data
PXDN- Name
- peroxidasin
- Type
- protein-coding
- Position
- 1,630,844–1,744,852 (−)
- Aliases
- ASGD7, COPOA, D2S448, D2S448E, MG50, PRG2, PXN, VPO, hsPxd01
- Ensembl
- ENSG00000130508
- RefSeq RNA
- NM_001446102.1, NM_001446103.1, NM_001446104.1, NM_001446105.1, NM_001446106.1
- RefSeq protein
- NP_001433031.1, NP_001433032.1, NP_001433033.1, NP_001433034.1, NP_001433035.1
This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis. [provided by RefSeq, Aug 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
peroxidasin
- Symbol
- PXDN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:1,630,844-1,744,852
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 33907
- exact match
- identifiers.org/ncbigene/7837
- found in taxon
- Homo sapiens
- genomic end
- 1748624
- genomic start
- 1635659
- chromosome
- human chromosome 2
- cytogenetic location
- 2p25.3
- expressed in
- adipose tissue
Sources (6)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Clinical significance
- References
- Further reading
Peroxidasin homolog is a protein that in humans is encoded by the PXDN gene.
Peroxidasin requires ionic bromine as a co-factor, making bromine an essential element for human life.
Excerpted from Wikipedia’s “PXDN” article, available under the CC BY-SA 4.0 licence.