QPCT
Sign in to saveAlso known as GCT, QC, sQC, glutaminyl-peptide cyclotransferase
Glutaminyl-peptide cyclotransferase is an enzyme that in humans is encoded by the QPCT gene.
Gene data
QPCT- Name
- glutaminyl-peptide cyclotransferase
- Type
- protein-coding
- Position
- 37,342,827–37,373,323 (+)
- Aliases
- GCT, QC, sQC
- Ensembl
- ENSG00000115828
- RefSeq RNA
- NM_012413.4
- RefSeq protein
- NP_036545.1
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
glutaminyl-peptide cyclotransferase
- Symbol
- QPCT
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:37,342,827-37,373,323
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein QPCT PDB 2afm.png
Show 7 more facts
- HomoloGene ID
- 8238
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/25797
- genomic end
- 37600465
- genomic start
- 37342827
- chromosome
- human chromosome 2
- cytogenetic location
- 2p22.2
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Glutaminyl-peptide cyclotransferase is an enzyme that in humans is encoded by the QPCT gene.
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.
Excerpted from Wikipedia’s “QPCT” article, available under the CC BY-SA 4.0 licence.