RAI14
Sign in to saveAlso known as NORPEG, RAI13, retinoic acid induced 14
Ankycorbin is an ankyrin repeat and coiled-coil domain containing protein that in humans is encoded by the RAI14 gene. It is expressed in a variety of human tissues and is thought to play a role in actin regulation of ectoplasmic specialization, establishment of sperm polarity and sperm adhesion. It may also promote the integrity of Sertoli cell tight junctions at the blood testis barrier.
Gene data
RAI14- Name
- retinoic acid induced 14
- Type
- protein-coding
- Position
- 34,655,566–34,832,613 (+)
- Aliases
- NORPEG, RAI13
- Ensembl
- ENSG00000039560
- RefSeq RNA
- NM_001145520.1, NM_001145521.2, NM_001145522.2, NM_001145523.2, NM_001145525.2
- RefSeq protein
- NP_001138992.1, NP_001138993.1, NP_001138994.1, NP_001138995.1, NP_001138997.1
Predicted to enable actin binding activity. Predicted to be involved in several processes, including apoptotic signaling pathway; regulation of NIK/NF-kappaB signaling; and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Molecular function
via MyGene.info
Gene · Ensembl
retinoic acid induced 14
- Symbol
- RAI14
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:34,655,566-34,832,613
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~4 min read
Encyclopedic overview
14 sectionsContents
- Gene
- Location
- Gene Neighborhood
- Expression
- Homology
- Paralogs
- Orthologs
- Protein
- Transcripts
- General Properties
- Structure and Domains
- Post Translational Modifications
- Function
- References
Ankycorbin is an ankyrin repeat and coiled-coil domain containing protein that in humans is encoded by the RAI14 gene. It is expressed in a variety of human tissues and is thought to play a role in actin regulation of ectoplasmic specialization, establishment of sperm polarity and sperm adhesion. It may also promote the integrity of Sertoli cell tight junctions at the blood testis barrier.
== Gene ==
Excerpted from Wikipedia’s “RAI14” article, available under the CC BY-SA 4.0 licence.