RALY

Also known as HNRPCL2, P542, RALY heterogeneous nuclear ribonucleoprotein

RNA-binding protein Raly is a protein that in humans is encoded by the RALY gene.

Gene data

RALY

Name: RALY heterogeneous nuclear ribonucleoprotein
Type: protein-coding
Position: 33,993,632–34,108,308 (+)
Aliases: HNRPCL2, P542
Ensembl: ENSG00000125970
RefSeq RNA: NM_007367.4, NM_016732.3, XM_005260334.6, XM_005260336.6, XM_011528695.4
RefSeq protein: NP_031393.2, NP_057951.1, XP_005260391.1, XP_005260393.1, XP_011526997.1

This gene encodes a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) gene family. This protein may play a role in pre-mRNA splicing and in embryonic development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011].

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II mRNA splicing, via spliceosome cholesterol homeostasis cholesterol homeostasis

Molecular function

nucleic acid binding transcription coregulator activity transcription coregulator activity RNA binding RNA binding RNA binding RNA binding protein binding

Cellular component

nucleus nucleus nucleus nucleus nucleoplasm catalytic step 2 spliceosome

via MyGene.info

Wikidata facts

Image: Protein RALY PDB 1wf1.png

Show 5 more facts

HomoloGene ID: 7216
exact match: identifiers.org/ncbigene/22913
genomic end: 32696114
genomic start: 32581452
cytogenetic location: 20q11.22

Sources (3)

via Wikidata · CC0

~1 min read

Article

2 sections

Contents

References
Further reading

RNA-binding protein Raly is a protein that in humans is encoded by the RALY gene.

In infectious mononucleosis, anti-EBNA-1 antibodies are produced which cross-react with multiple normal human proteins. The cross-reactivity is due to anti-gly/ala antibodies that cross-react with host proteins containing configurations like those in the EBNA-1 repeat. One such antigen is RALY which is a member of the heterogeneous nuclear ribonucleoprotein gene family.