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GeneQ18034286· pop 5· linked from 3 articles

Also known as NGAP, RAS protein activator like 2

Ras GTPase-activating protein nGAP is an enzyme that in humans is encoded by the RASAL2 gene.

Gene data

RASAL2
Name
RAS protein activator like 2
Type
protein-coding
Aliases
NGAP

This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Wikidata facts

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HomoloGene ID
35217
genomic end
178448644
genomic start
178094104
cytogenetic location
1q25.2
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Ras GTPase-activating protein nGAP is an enzyme that in humans is encoded by the RASAL2 gene.

This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

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