RC3H1
Sign in to saveAlso known as RNF198, ROQUIN, ring finger and CCCH-type domains 1, FHL6, IMDSHY
Ring finger and CCCH-type domains 1, also known as Roquin-1, is a protein that in humans is encoded by the RC3H1 gene.
Gene data
RC3H1- Name
- ring finger and CCCH-type domains 1
- Type
- protein-coding
- Position
- 173,931,084–174,022,418 (−)
- Aliases
- FHL6, IMDSHY, RNF198, ROQUIN
- Ensembl
- ENSG00000135870
- RefSeq RNA
- NM_001300850.1, NM_001300851.1, NM_001300852.1, NM_172071.4, XM_005244921.4
- RefSeq protein
- NP_001287779.1, NP_001287780.1, NP_001287781.1, NP_742068.1, XP_005244978.1
This gene encodes a protein containing RING-type and C3H1-type zinc finger motifs. The encoded protein recognizes and binds to a constitutive decay element (CDE) in the 3' UTR of mRNAs, leading to mRNA deadenylation and degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
ring finger and CCCH-type domains 1
- Symbol
- RC3H1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:173,931,084-174,022,418
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 19036
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/149041
- genomic end
- 174022357
- genomic start
- 173931084
- chromosome
- human chromosome 1
- cytogenetic location
- 1q25.1
- expressed in
- trabecular bone
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Ring finger and CCCH-type domains 1, also known as Roquin-1, is a protein that in humans is encoded by the RC3H1 gene.
== Function ==
Excerpted from Wikipedia’s “RC3H1” article, available under the CC BY-SA 4.0 licence.