Gene data
RINT1- Name
- RAD50 interactor 1
- Type
- protein-coding
- Position
- 105,532,116–105,569,207 (+)
- Aliases
- ILFS3, RINT-1
- Ensembl
- ENSG00000135249
- RefSeq RNA
- NM_001346599.2, NM_001346600.2, NM_001346601.2, NM_001346603.2, NM_001445595.1
- RefSeq protein
- NP_001333528.1, NP_001333529.1, NP_001333530.1, NP_001333532.1, NP_001432524.1
This gene encodes a protein first identified for its ability to interact with the RAD50 double strand break repair protein, with the resulting interaction implicated in the regulation of cell cycle progression and telomere length. The encoded protein may also play a role in trafficking of cellular cargo from the endosome to the trans-Golgi network. Mutations in this gene may be associated with breast cancer in human patients. [provided by RefSeq, Oct 2016].
Gene Ontology
Biological process
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulumretrograde vesicle-mediated transport, Golgi to endoplasmic reticulumretrograde vesicle-mediated transport, Golgi to endoplasmic reticulummitotic G2 DNA damage checkpoint signalingregulation of ER to Golgi vesicle-mediated transport
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RAD50 interactor 1
- Symbol
- RINT1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:105,532,116-105,569,207
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 11070
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/60561
- genomic end
- 105208124
- genomic start
- 105532169
- chromosome
- human chromosome 7
- cytogenetic location
- 7q22.3
Sources (4)
via Wikidata · CC0