RIPOR2
Sign in to saveAlso known as C6orf32, DIFF40, DIFF48, MYONAP, PL48, FAM65B, DFNB104, family with sequence similarity 65 member B
RHO family interacting cell polarization regulator 2 is a protein that in humans is encoded by the RIPOR2 gene.
Gene data
RIPOR2- Name
- RHO family interacting cell polarization regulator 2
- Type
- protein-coding
- Position
- 24,803,362–25,042,170 (−)
- Aliases
- C6orf32, DFNA21, DFNB104, DIFF40, DIFF48, FAM65B, MYONAP, PL48
- Ensembl
- ENSG00000111913
- RefSeq RNA
- NM_001286445.3, NM_001286446.3, NM_001286447.2, NM_001346031.2, NM_001346032.2
- RefSeq protein
- NP_001273374.1, NP_001273375.1, NP_001273376.1, NP_001332960.1, NP_001332961.1
This gene encodes an atypical inhibitor of the small G protein RhoA. Inhibition of RhoA activity by the encoded protein mediates myoblast fusion and polarization of T cells and neutrophils. The encoded protein is a component of hair cell stereocilia that is essential for hearing. A splice site mutation in this gene results in hearing loss in human patients. [provided by RefSeq, Sep 2016].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RHO family interacting cell polarization regulator 2
- Symbol
- RIPOR2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:24,803,362-25,042,170
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 9284
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9750
- chromosome
- human chromosome 6
- genomic start
- 24804282
- genomic end
- 25042170
- cytogenetic location
- 6p22.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
RHO family interacting cell polarization regulator 2 is a protein that in humans is encoded by the RIPOR2 gene.
== Function ==
Excerpted from Wikipedia’s “RIPOR2” article, available under the CC BY-SA 4.0 licence.