Structure via PubChem · Public domain (PubChem)
rodiasine
Sign in to saveRodiasine is a cyclic bisbenzylisoquinoline alkaloid that was first isolated from the South American greenheart tree Chlorocardium rodiei. The synthesis of O-demethylrodiasine (antioquine) and its derivatives, and the possible application of these compounds as anti-cancer, calcium channel blockers, and anti-parasitic drugs has been described.
In the Vinony graph
Within Vinony's link graph, rodiasine is referenced by 3 other articles, and connects out to digital object identifier, chemical formula and alkaloid.
It is catalogued under topics including Benzylisoquinoline alkaloids and Chembox image size set.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C38H42N2O6
- Molecular weight
- 622.7 g/mol
- IUPAC name
- (1R,14S)-9,20,21,25-tetramethoxy-15,30-dimethyl-23-oxa-15,30-diazaheptacyclo[22.6.2.13,7.18,12.114,18.027,31.022,33]pentatriaconta-3(35),4,6,8,10,12(34),18,20,22(33),24,26,31-dodecaen-6-ol
- SMILES
- CN1CCC2=CC(=C3C=C2[C@H]1CC4=CC(=C(C=C4)O)C5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
- InChIKey
- HIQZXOFBXJICTD-IHLOFXLRSA-N
- XLogP
- 6.4
- Polar surface area
- 72.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- isoquinoline alkaloid
- Mass
- 622.304287
Show 4 more facts
- chemical formula
- C₃₈H₄₂N₂O₆
- isomeric SMILES
- CN1CCC2=CC(=C3C=C2[C@H]1CC4=CC(=C(C=C4)O)C5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
- canonical SMILES
- CN1CCC2=CC(=C3C=C2C1CC4=CC(=C(C=C4)O)C5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)OC)OC
- described by source
- Encyclopædia Britannica 11th edition
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Rodiasine is a cyclic bisbenzylisoquinoline alkaloid that was first isolated from the South American greenheart tree Chlorocardium rodiei. The synthesis of O-demethylrodiasine (antioquine) and its derivatives, and the possible application of these compounds as anti-cancer, calcium channel blockers, and anti-parasitic drugs has been described.
== References ==
Excerpted from Wikipedia’s “rodiasine” article, available under the CC BY-SA 4.0 licence.