RUFY1
Sign in to saveAlso known as RABIP4, ZFYVE12, RUN and FYVE domain containing 1
RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene. It is named after the RUN and FYVE domains it contains.
Gene data
RUFY1- Name
- RUN and FYVE domain containing 1
- Type
- protein-coding
- Position
- 179,550,542–179,610,015 (+)
- Aliases
- RABIP4, ZFYVE12
- Ensembl
- ENSG00000176783
- RefSeq RNA
- NM_001040451.3, NM_001040452.3, NM_025158.5, XM_005265993.5, XM_006714921.4
- RefSeq protein
- NP_001035541.1, NP_001035542.1, NP_079434.3, XP_005266050.1, XP_006714984.2
This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
RUN and FYVE domain containing 1
- Symbol
- RUFY1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HG30_PATCH:315,196-376,273
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein RUFY1 PDB 2YQM.png
Show 7 more facts
- HomoloGene ID
- 23522
- exact match
- identifiers.org/ncbigene/80230
- genomic start
- 179550554
- found in taxon
- Homo sapiens
- genomic end
- 179610012
- chromosome
- human chromosome 5
- cytogenetic location
- 5q35.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene. It is named after the RUN and FYVE domains it contains.
== Interactions ==
Excerpted from Wikipedia’s “RUFY1” article, available under the CC BY-SA 4.0 licence.