S100A8

Name

S100 calcium binding protein A8

Type

protein-coding

Position

153,390,018–153,422,638 (−)

Aliases

60B8AG, CAGA, CFAG, CGLA, CP-10, L1Ag, MA387, MRP8, NIF, P8

Ensembl

ENSG00000143546

RefSeq RNA

NM_001319196.1, NM_001319197.1, NM_001319198.2, NM_001319201.2, NM_002964.5

RefSeq protein

NP_001306125.1, NP_001306126.1, NP_001306127.1, NP_001306130.1, NP_002955.2

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016].

via MyGene.info

Gene · Ensembl

S100 calcium binding protein A8

Symbol

S100A8

Biotype

Protein coding

Organism

Homo sapiens

Location

1:153,390,018-153,422,638

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein S100A8 PDB 1mr8.png

via Wikidata · CC0