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EntityQ7434451· pop 5· linked from 9 articles

Scopine is a tropane alkaloid found in a variety of plants including Mandragora root, Senecio mikanioides (Delairea odorata), Scopolia carniolica, and Scopolia lurida.

Wikidata facts

Mass
155.094628656
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canonical SMILES
CN1C2CC(O)CC1C1OC12
isomeric SMILES
O[C@@H]1C[C@H]2N(C)[C@@H](C1)[C@@H]3O[C@H]23
chemical formula
C₈H₁₃NO₂
Commons category
Scopine
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Contents
  • Alkaloids
  • References

Scopine is a tropane alkaloid found in a variety of plants including Mandragora root, Senecio mikanioides (Delairea odorata), Scopolia carniolica, and Scopolia lurida.

Scopine can be prepared by the hydrolysis of scopolamine. It can also be prepared in three steps from N-methoxycarbonylpyrrole and 1,1,3,3-tetrabromoacetone; the reagents are combined in a [4+3] cycloaddition, followed by a diastereoselective reduction with diisobutylaluminum hydride, and finally a Prilezhaev epoxidation with trifluoroperacetic acid affords scopine.

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