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GeneQ18040304· pop 6· linked from 3 articles

SFMBT1

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Also known as RU1, SFMBT, hSFMBT, Scm-like with four mbt domains 1, Scm like with four mbt domains 1

Scm-like with four mbt domains 1 is a protein that in humans is encoded by the SFMBT1 gene.

Gene data

SFMBT1
Name
Scm like with four mbt domains 1
Type
protein-coding
Position
52,903,345–53,046,750 (−)
Aliases
RU1, SFMBT, hSFMBT
Ensembl
ENSG00000163935
RefSeq RNA
NM_001005158.2, NM_001005159.2, NM_016329.4
RefSeq protein
NP_057413.2

This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012].

Gene Ontology

via MyGene.info

Gene · Ensembl

Scm like with four mbt domains 1

Symbol
SFMBT1
Biotype
Protein coding
Organism
Homo sapiens
Location
3:52,903,345-53,046,750
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
9472
genomic start
52937588
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/51460
genomic end
53080766
chromosome
human chromosome 3
cytogenetic location
3p21.1
expressed in
islet of Langerhans
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections
Contents
  • Function
  • References
  • Further reading

Scm-like with four mbt domains 1 is a protein that in humans is encoded by the SFMBT1 gene.

==Function== This gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. It encodes a protein which contains four malignant brain tumor repeat (mbt) domains and may be involved in antigen recognition. [provided by RefSeq, Jun 2012]. It encodes a transcriptional repressor protein. The SFMBT1 protein's interaction with cancers is unclear, but elevated levels have been recorded in some renal cancers.

Excerpted from Wikipedia’s “SFMBT1” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0