SH3GL1

Also known as CNSA1, EEN, SH3D2B, SH3P8, SH3 domain containing GRB2 like 1, endophilin A2

Endophilin-A2 is a protein that in humans is encoded by the SH3GL1 gene.

In the Vinony graph

Within Vinony's link graph, SH3GL1 is referenced by 4 other articles, and connects out to Q180686, human chromosome 19 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 19.

Its subject is documented across 6 Wikipedia language editions.

Gene data

SH3GL1

Name: SH3 domain containing GRB2 like 1, endophilin A2
Type: protein-coding
Position: 4,360,367–4,400,573 (−)
Aliases: CNSA1, EEN, SH3D2B, SH3P8
Ensembl: ENSG00000141985
RefSeq RNA: NM_001199943.2, NM_001199944.2, NM_003025.4, XM_017027146.2, XM_047439222.1
RefSeq protein: NP_001186872.1, NP_001186873.1, NP_003016.1, XP_016882635.1, XP_047295178.1

This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].