SLAMF7
Sign in to saveAlso known as 19A, CD319, CRACC, CS1, SLAM family member 7
SLAM family member 7 is a protein that in humans is encoded by the SLAMF7 gene.
Gene data
SLAMF7- Name
- SLAM family member 7
- Type
- protein-coding
- Position
- 160,739,057–160,754,821 (+)
- Aliases
- 19A, CD319, CRACC, CS1
- Ensembl
- ENSG00000026751
- RefSeq RNA
- NM_001282588.2, NM_001282589.2, NM_001282590.2, NM_001282591.2, NM_001282592.2
- RefSeq protein
- NP_001269517.1, NP_001269518.1, NP_001269519.1, NP_001269520.1, NP_001269521.1
Enables identical protein binding activity. Predicted to be involved in adaptive immune response. Predicted to act upstream of or within regulation of natural killer cell activation. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
SLAM family member 7
- Symbol
- SLAMF7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:160,739,057-160,754,821
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 49660
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/57823
- chromosome
- human chromosome 1
- genomic start
- 160709037
- genomic end
- 160724611
- cytogenetic location
- 1q23.3
- expressed in
- blood
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
SLAM family member 7 is a protein that in humans is encoded by the SLAMF7 gene.
The surface antigen CD319 (SLAMF7) is a robust marker of normal plasma cells and malignant plasma cells in multiple myeloma. In contrast to CD138 (the traditional plasma cell marker), CD319/SLAMF7 is much more stable and allows robust isolation of malignant plasma cells from delayed or even cryopreserved samples.
Excerpted from Wikipedia’s “SLAMF7” article, available under the CC BY-SA 4.0 licence.