SLC45A3
Sign in to saveAlso known as IPCA-2, IPCA-6, IPCA-8, IPCA6, PCANAP2, PCANAP6, PCANAP8, PRST
Solute carrier family 45 member 3 (SLC45A3), also known as prostate cancer-associated protein 6 or prostein, is a protein that in humans is encoded by the SLC45A3 gene.
Gene data
SLC45A3- Name
- solute carrier family 45 member 3
- Type
- protein-coding
- Position
- 205,657,851–205,680,990 (−)
- Aliases
- IPCA-2, IPCA-6, IPCA-8, IPCA6, PCANAP2, PCANAP6, PCANAP8, PRST
- Ensembl
- ENSG00000158715
- RefSeq RNA
- NM_033102.3
- RefSeq protein
- NP_149093.1
Predicted to enable sucrose:proton symporter activity. Predicted to be involved in positive regulation of small molecule metabolic process; regulation of oligodendrocyte differentiation; and sucrose transport. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
solute carrier family 45 member 3
- Symbol
- SLC45A3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:205,657,851-205,680,990
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 23813
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/85414
- genomic end
- 205680509
- genomic start
- 205626979
- chromosome
- human chromosome 1
- cytogenetic location
- 1q32.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Regulation
- References
- Further reading
Solute carrier family 45 member 3 (SLC45A3), also known as prostate cancer-associated protein 6 or prostein, is a protein that in humans is encoded by the SLC45A3 gene.
SLC45A3 is expressed in a prostate-specific manner by normal tissues and at a significantly lower level in prostate tumor cell lines. Treatment of prostate cancer cell lines with androgens upregulates the expression of SLC45A3.
Excerpted from Wikipedia’s “SLC45A3” article, available under the CC BY-SA 4.0 licence.