Also known as MRSR, SPMSY, SRS, SpS, spermine synthase, MRXSSR
protein-coding gene in the species Homo sapiens
Gene data
SMS- Name
- spermine synthase
- Type
- protein-coding
- Chromosome
- X
- Position
- 21,940,557–21,994,837 (+)
- Aliases
- MRSR, MRXSSR, SPMSY, SRS, SpS
- Ensembl
- ENSG00000102172
- RefSeq RNA
- NM_001258423.2, NM_004595.5, XM_005274582.3, XM_011545568.3, XM_054327621.1
- RefSeq protein
- NP_001245352.1, NP_004586.2, XP_005274639.1, XP_011543870.1, XP_054183596.1
This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017].
Gene Ontology
Biological process
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
spermine synthase
- Symbol
- SMS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:21,940,557-21,994,837
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein SMS PDB 3C6K.png
Show 8 more facts
- HomoloGene ID
- 88709
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/6611
- chromosome
- human X chromosome
- genomic end
- 21994837
- genomic start
- 21940709
- cytogenetic location
- Xp22.11
- expressed in
- ovary
Sources (8)
via Wikidata · CC0