SNRNP200

Also known as ASCC3L1, BRR2, HELIC2, RP33, U5-200KD, small nuclear ribonucleoprotein U5 subunit 200

U5 small nuclear ribonucleoprotein 200 kDa helicase is an enzyme that in humans is encoded by the SNRNP200 gene.

In the Vinony graph

Within Vinony's link graph, SNRNP200 is referenced by 27 other articles, and connects out to Q180686, Ensembl genome database project and human.

It is catalogued under topics including Genes on human chromosome 2 and Spliceosome.

Its subject is documented across 6 Wikipedia language editions.

Gene data

SNRNP200

Name: small nuclear ribonucleoprotein U5 subunit 200
Type: protein-coding
Aliases: ASCC3L1, BRR2, HELIC2, RP33, U5-200KD

Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010].

via MyGene.info