SREK1
Sign in to saveAlso known as SFRS12, SRrp508, SRrp86, splicing regulatory glutamic acid/lysine-rich protein 1, splicing regulatory glutamic acid and lysine rich protein 1
Splicing factor, arginine/serine-rich 12 is a protein that in humans is encoded by the SFRS12 gene.
Gene data
SREK1- Name
- splicing regulatory glutamic acid and lysine rich protein 1
- Type
- protein-coding
- Position
- 66,139,971–66,183,615 (+)
- Aliases
- SFRS12, SRrp508, SRrp86
- Ensembl
- ENSG00000153914
- RefSeq RNA
- NM_001077199.3, NM_001270492.2, NM_001270493.1, NM_001323527.2, NM_001323529.2
- RefSeq protein
- NP_001070667.1, NP_001257421.1, NP_001310456.1, NP_001310458.1, NP_001310462.1
This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
Gene Ontology
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
splicing regulatory glutamic acid and lysine rich protein 1
- Symbol
- SREK1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:66,139,971-66,183,615
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 10581
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/140890
- genomic end
- 65479443
- genomic start
- 65435799
- chromosome
- human chromosome 5
- cytogenetic location
- 5q12.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Splicing factor, arginine/serine-rich 12 is a protein that in humans is encoded by the SFRS12 gene.
SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002).[supplied by OMIM]
Excerpted from Wikipedia’s “SREK1” article, available under the CC BY-SA 4.0 licence.