SRGAP2
Sign in to saveAlso known as ARHGAP34, FNBP2, SRGAP2A, SRGAP3, SLIT-ROBO Rho GTPase activating protein 2
جين من أنواع جينات الإنسان العاقل
Gene data
SRGAP2- Name
- SLIT-ROBO Rho GTPase activating protein 2
- Type
- protein-coding
- Position
- 206,203,346–206,464,436 (+)
- Aliases
- ARHGAP34, FNBP2, SRGAP2A
- Ensembl
- ENSG00000266028
- RefSeq RNA
- NM_001042758.1, NM_001170637.4, NM_001300952.2, NM_001377444.1, NM_001377445.1
- RefSeq protein
- NP_001164108.1, NP_001287881.1, NP_001364373.1, NP_001364374.1, NP_001364375.1
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
SLIT-ROBO Rho GTPase activating protein 2
- Symbol
- SRGAP2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:206,203,346-206,464,436
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 52683
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23380
- chromosome
- human chromosome 1
- genomic start
- 206203346
- genomic end
- 206464436
- cytogenetic location
- 1q32.1
- expressed in
- monocyte
Sources (3)
via Wikidata · CC0
Article · العربية
SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2) هوَ بروتين يُشَفر بواسطة جين SRGAP2 في الإنسان.
Abstract from DBpedia / Wikipedia · CC BY-SA