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GeneQ18031725· pop 7· linked from 5 articles

Also known as TRAPA, signal sequence receptor subunit 1

Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene.

Gene data

SSR1
Name
signal sequence receptor subunit 1
Type
protein-coding
Position
7,268,306–7,347,446 (−)
Aliases
TRAPA
RefSeq RNA
NM_001292008.2, NM_001444973.1, NM_003144.5, NR_120448.2
RefSeq protein
NP_001278937.1, NP_001431902.1, NP_003135.2

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014].

via MyGene.info

Gene · Ensembl

signal sequence receptor subunit 1

Symbol
SSR1
Biotype
Protein coding
Organism
Homo sapiens
Location
6:7,268,306-7,347,446
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
2368
found in taxon
Homo sapiens
genomic end
7347679
genomic start
7268539
cytogenetic location
6p24.3
expressed in
gums
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene.

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.

Excerpted from Wikipedia’s “SSR1” article, available under the CC BY-SA 4.0 licence.

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