STAMBP
Sign in to saveAlso known as AMSH, MICCAP, STAM binding protein
STAM-binding protein is a protein that in humans is encoded by the STAMBP gene.
Gene data
STAMBP- Name
- STAM binding protein
- Type
- protein-coding
- Position
- 73,828,916–73,873,670 (+)
- Aliases
- AMSH, MICCAP
- Ensembl
- ENSG00000124356
- RefSeq RNA
- NM_001353967.2, NM_001353968.2, NM_001353969.2, NM_001353970.2, NM_001353971.2
- RefSeq protein
- NP_001340896.1, NP_001340897.1, NP_001340898.1, NP_001340899.1, NP_001340900.1
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
STAM binding protein
- Symbol
- STAMBP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:73,828,916-73,873,670
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 3 more facts
- HomoloGene ID
- 4719
- exact match
- identifiers.org/ncbigene/10617
- found in taxon
- Homo sapiens
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- Interactions
- References
- Further reading
STAM-binding protein is a protein that in humans is encoded by the STAMBP gene.
== Function ==
Excerpted from Wikipedia’s “STAMBP” article, available under the CC BY-SA 4.0 licence.