SYCP3
Sign in to saveAlso known as COR1, SCP3, SPGF4, RPRGL4, synaptonemal complex protein 3
Synaptonemal complex protein 3 is a protein that in humans is encoded by the SYCP3 gene. It is a component of the synaptonemal complex formed between homologous chromosomes during the prophase of meiosis.
Gene data
SYCP3- Name
- synaptonemal complex protein 3
- Type
- protein-coding
- Aliases
- COR1, RPRGL4, SCP3, SPGF4
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010].
via MyGene.info
Gene · Ensembl
synaptonemal complex protein 3
- Symbol
- SYCP3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:101,728,646-101,739,534
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7964
- exact match
- identifiers.org/ncbigene/50511
- genomic end
- 102133250
- genomic start
- 102122426
- cytogenetic location
- 12q23.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Gene family
- References
- Further reading
- External links
Synaptonemal complex protein 3 is a protein that in humans is encoded by the SYCP3 gene. It is a component of the synaptonemal complex formed between homologous chromosomes during the prophase of meiosis.
== Gene family == {|style="float:left; margin-right: 0.5em" | |} SYCP3 is also known as COR1. It contains a conserved coiled-coil domain that is also found in the FAM9 (FAM9A, FAM9B) family of proteins, found on the human X chromosome.