SYNPO2
Sign in to saveAlso known as synaptopodin 2, SYISL
Myopodin protein, also called Synaptopodin-2 is a protein that in humans is encoded by the SYNPO2 gene. Myopodin is expressed in cardiac, smooth muscle and skeletal muscle, and localizes to Z-disc structures.
Gene data
SYNPO2- Name
- synaptopodin 2
- Type
- protein-coding
- Position
- 118,850,688–119,101,481 (+)
- Ensembl
- ENSG00000172403
- RefSeq RNA
- NM_001128933.3, NM_001128934.3, NM_001286754.2, NM_001286755.2, NM_001389263.1
- RefSeq protein
- NP_001122405.1, NP_001122406.1, NP_001273683.1, NP_001273684.1, NP_001376192.1
Enables alpha-actinin binding activity and filamin binding activity. Involved in positive regulation of actin filament bundle assembly; positive regulation of cell migration; and regulation of Rho-dependent protein serine/threonine kinase activity. Located in several cellular components, including Z disc; focal adhesion; and stress fiber. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
synaptopodin 2
- Symbol
- SYNPO2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:118,850,688-119,101,481
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 15400
- genetic association
- ALS
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/171024
- genomic start
- 119809996
- chromosome
- human chromosome 4
- genomic end
- 119982402
- cytogenetic location
- 4q26
- expressed in
- pericardium
via Wikidata · CC0
~2 min read
Encyclopedic overview
5 sectionsContents
- Structure
- Function
- Interactions
- References
- Further reading
Myopodin protein, also called Synaptopodin-2 is a protein that in humans is encoded by the SYNPO2 gene. Myopodin is expressed in cardiac, smooth muscle and skeletal muscle, and localizes to Z-disc structures.
== Structure ==
Excerpted from Wikipedia’s “SYNPO2” article, available under the CC BY-SA 4.0 licence.