TACC2
Sign in to saveAlso known as AZU-1, ECTACC, transforming acidic coiled-coil containing protein 2
Transforming acidic coiled-coil-containing protein 2 is a protein that in humans is encoded by the TACC2 gene.
Gene data
TACC2- Name
- transforming acidic coiled-coil containing protein 2
- Type
- protein-coding
- Position
- 121,989,163–122,254,560 (+)
- Aliases
- AZU-1, ECTACC
- Ensembl
- ENSG00000138162
- RefSeq RNA
- NM_001291876.2, NM_001291877.2, NM_001291878.2, NM_001291879.2, NM_001438364.1
- RefSeq protein
- NP_001278805.2, NP_001278806.2, NP_001278807.1, NP_001278808.1, NP_001425293.1
Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
transforming acidic coiled-coil containing protein 2
- Symbol
- TACC2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:121,989,163-122,254,560
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- HomoloGene ID
- 5087
- genetic association
- myopia
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10579
- genomic end
- 124014060
- genomic start
- 121989163
- chromosome
- human chromosome 10
- cytogenetic location
- 10q26.13
- expressed in
- glutes
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Transforming acidic coiled-coil-containing protein 2 is a protein that in humans is encoded by the TACC2 gene.
Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin.
Excerpted from Wikipedia’s “TACC2” article, available under the CC BY-SA 4.0 licence.