tanespimycin
Sign in to saveAlso known as 17-AAG, 17-allylamino-17-demethoxygeldanamycin, 17-N-allylamino-17-demethoxygeldanamycin, 17AAG
Tanespimycin ('17-N-allylamino-17-demethoxygeldanamycin, 17-AAG') is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, specifically in younger patients with certain types of leukemia or solid tumors, especially kidney tumors.
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Encyclopedic overview
3 sectionsContents
- Clinical trials
- References
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Tanespimycin ('17-N-allylamino-17-demethoxygeldanamycin, 17-AAG') is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, specifically in younger patients with certain types of leukemia or solid tumors, especially kidney tumors.
It works by inhibiting Hsp90, which is expressed in those tumors.
Excerpted from Wikipedia’s “tanespimycin” article, available under the CC BY-SA 4.0 licence.