Teschovirus

Teschovirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Pigs serve as natural hosts. There are two species in this genus, including Porcine teschovirus, which is responsible for the porcine enteroviral encephalomyelitis disease caused in pigs. The genus name comes from this species and the disease it causes: Teschen disease (a severe and fatal form of pig encephalomyelitis), which itself was named for the town Teschen in Poland/Czechoslovakia where the disease was first recognised in 1929.

==Genome== Teschovirus has a single-stranded, linear, non-segmented RNA genome. The RNA genome is positively sensed meaning that it has the same polarity as the mRNA and no reverse transcription is necessary. The size of the genome is between 7000 and 9000 nucleotides long. In addition the virus genome contains at the 5' end a protein called VPg and the 3' end is polyadenylated. Through translation of the genome a polyprotein is produced. It is later cleaved in order to give twelve proteins. These proteins are nucleoproteins, non-structural proteins, a polymerase, proteases like the leader protein and the genome linked-protein.